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MLH1 Polyclonal Antibody, 100ul Rotator RTN4 belongs to the family

SKU: 29928486870

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MLH1 Polyclonal Antibody, 100ul Rotator RTN4 belongs to the familyMLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full length natures have not

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Description

RTN4 belongs to the family of reticulon encoding genes

This gene encodes the basic transcription factor 3

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP

Alzheimer's disease and Crohn's disease

It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin| pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160

MLH1 Polyclonal Antibody, 100ul Rotator RTN4 belongs to the familyMLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full length natures have not

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