UAP1L Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction The protein encoded by MED27

The protein encoded by MED27 (mediator complex subunit 27) is a subunit of the CRSP (cofactor required for SP1 activation) complex

Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure

the second and third exons are the immunoglobulin lambda joining 1 and the immunoglobulin lambda constant 1 gene segments

Required for stabilization of KCNH1 channels at the cell membrane (PubMed: 23144454)

Binding of the ligand activates the cytolytic response of natural killer (NK) cells

UAP1L Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction The protein encoded by MED27