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Cbl Polyclonal Antibody, 100ul[BT-AP01263] Biomatrix Mutations in this gene are

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Cbl Polyclonal Antibody, 100ul[BT-AP01263] Biomatrix Mutations in this gene areCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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Description

Mutations in this gene are associated with Meckel syndrome type 8

This gene encodes a type IV collagen alpha protein

the upstream non-AUG (CUG) and downstream AUG codons

Contains 4 cortactin repeats

Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor

Cbl Polyclonal Antibody, 100ul[BT-AP01263] Biomatrix Mutations in this gene areCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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