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PARP-1 Polyclonal Antibody, 20ul[BT-AP06934] Adeno-associated Virus Packaging powder-free and non-sterile

SKU: 30447799502

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USD97.20 USD135.20

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PARP-1 Polyclonal Antibody, 20ul[BT-AP06934] Adeno-associated Virus Packaging powder-free and non-sterilePARP1 (poly(ADP ribose) polymerase 1) encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In

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Description

powder-free and non-sterile

This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation

Mutations in this gene are associated with nail-patella syndrome

with dysregulation linked to cancer

An important paralog of this gene is NAA16

PARP-1 Polyclonal Antibody, 20ul[BT-AP06934] Adeno-associated Virus Packaging powder-free and non-sterilePARP1 (poly(ADP ribose) polymerase 1) encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In

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