ANTR2 Polyclonal Antibody, 20ul Site-directed Mutagenesis These proteins transduce their signals

These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD

The protein localizes to the plasma membrane and pericentrosomal vesicles

This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

At least three transcript variants encoding different isoforms have been found for this gene

This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development

ANTR2 Polyclonal Antibody, 20ul Site-directed Mutagenesis These proteins transduce their signalsThis gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.