Nrf2 Polyclonal Antibody, 20ul[BT-AP06175] ADME Mutations in this gene result

Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions

studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras

as well as in disease processes

Alternate allele-specific splice variants

formerly thought to be a truncated version of beta chain (B2t)

Nrf2 Polyclonal Antibody, 20ul[BT-AP06175] ADME Mutations in this gene resultNFE2L2 encodes a transcription factor (nuclear factor, erythroid 2 like 2) which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different