CD58 Polyclonal Antibody, 50ul[BT-AP01518] Monoclonal Antibody Preparation This gene is localized to

This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes

Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR)

and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function

An important paralog of RABEP2 is RABEP1

and cancer predisposition

CD58 Polyclonal Antibody, 50ul[BT-AP01518] Monoclonal Antibody Preparation This gene is localized toCD58 encodes a member of the immunoglobulin superfamily. CD58 molecule is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.