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Frizzled-10 Polyclonal Antibody, 50ul[BT-AP03356] Petri Dishes 2007 [PubMed: 17947679])

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Frizzled-10 Polyclonal Antibody, 50ul[BT-AP03356] Petri Dishes 2007 [PubMed: 17947679])FZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.

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Description

2007 [PubMed: 17947679])

Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9)

Cleavage of fibronectin and laminin leads to cell detachment and apoptosis

The receptors of IL15 and IL2 share two subunits

Contains 10 C2H2-type zinc fingers

Frizzled-10 Polyclonal Antibody, 50ul[BT-AP03356] Petri Dishes 2007 [PubMed: 17947679])FZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.

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