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GGCT Polyclonal Antibody, 50ul Measuring Instruments PTEN (phosphatase and tensin homolog)

SKU: 3114721355

4.3
USD185.00 USD217.00

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GGCT Polyclonal Antibody, 50ul Measuring Instruments PTEN (phosphatase and tensin homolog)The protein encoded by this gene catalyzes the formation of 5 oxoproline from gamma glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20.

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Description

PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency

This protein is involved in cargo-specific control of clathrin-mediated endocytosis

The protein encoded by EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) is the fourth

which heterodimerizes with type I keratins to form hair and nails

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

GGCT Polyclonal Antibody, 50ul Measuring Instruments PTEN (phosphatase and tensin homolog)The protein encoded by this gene catalyzes the formation of 5 oxoproline from gamma glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20.

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