CNOT6 Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos sister chromatid cohesion is released

sister chromatid cohesion is released in 2 steps via distinct mechanisms

Interacts with RHOT1/Miro-1 and RHOT2/Miro-2

this receptor likely has a multimeric structure

a type I keratin

This gene is biallelically expressed in the brain| however| only the paternal allele is expressed in the testis (PMID:18055845)

CNOT6 Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos sister chromatid cohesion is releasedThis gene encodes the catalytic component of the CCR4 NOT core transcriptional regulation complex. The encoded protein has a 3' 5' RNase activity and prefers polyadenylated substrates. The CCR4 NOT complex plays a role in many cellular processes including miRNA mediated repression mRNA degradation and transcriptional regulation.