PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome The protein encoded by this

The protein encoded by this gene mediates calcium entry| and this entry is potentiated by calcium store depletion

Interacts with the PDZ domain of SHANK1

resulting in downregulation of their active form

the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase

Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2

PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome The protein encoded by thisPRKD1 is a serine threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009