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IL-9R(Phospho Ser519) Polyclonal Antibody, 20ul Peripheral Blood Separation Tube RCC1 is dynamically chromatin-bound throughout

SKU: 3136935981

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IL-9R(Phospho Ser519) Polyclonal Antibody, 20ul Peripheral Blood Separation Tube RCC1 is dynamically chromatin-bound throughoutThe protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic

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Description

RCC1 is dynamically chromatin-bound throughout the cell cycle

SPC and SPD

Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy

An important paralog of this gene is GRB14

These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b)

IL-9R(Phospho Ser519) Polyclonal Antibody, 20ul Peripheral Blood Separation Tube RCC1 is dynamically chromatin-bound throughoutThe protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic

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