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Akt1 Polyclonal Antibody, 50ul[BT-AP00342] Microbial Genome Editing Two alternatively spliced transcript variants

SKU: 31448983019

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Akt1 Polyclonal Antibody, 50ul[BT-AP00342] Microbial Genome Editing Two alternatively spliced transcript variantsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Two alternatively spliced transcript variants that encode different proteins have been described for this gene

The first step involves recognition of the TATA element by the TATA-binding subunit (TBP

both early in development as well as in later stages

also known as epilepsy

this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function

Akt1 Polyclonal Antibody, 50ul[BT-AP00342] Microbial Genome Editing Two alternatively spliced transcript variantsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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