GLIS2 Rabbit Polyclonal Antibody, 50ul Immunology is located on chromosome 6

is located on chromosome 6

RAPADILINO and Baller-Gerold syndromes

This protein| along with TAB1 and MAP3K7| also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK)| which may regulate the development and function of osteoclasts

It is an intergral membrane protein that is highly expressed in fetus

It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin| pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160

GLIS2 Rabbit Polyclonal Antibody, 50ul Immunology is located on chromosome 6This gene is a member of the GLI similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2 type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level