Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene cause

Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma

Belongs to the alkB family

when overexpressed

a dimerization domain

it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul

Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene causeAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the