Bovine Toll-like Receptor 4, TLR4 ELISA Kit, 96T Serum The 206 amino acid precursor
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Bovine Toll-like Receptor 4, TLR4 ELISA Kit, 96T Serum The 206 amino acid precursorCooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed: 17559944). Acts via MYD88, TIRAP and TRAF6, leading to NF kappa B activation, cytokine secretion and the inflammatory response. Also involved in LPS independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes macrophages in response to oxidized low
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