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NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05997] Polyclonal Antibody Preparation This gene encodes a member

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NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05997] Polyclonal Antibody Preparation This gene encodes a memberNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of RELA, RELA. Four

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Description

This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit

Additional variants have been found but their full-length nature has not been determined

This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1

Inhibits the transcriptional activation mediated by PAX5

The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and| when overexpressed| induces apoptosis

NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05997] Polyclonal Antibody Preparation This gene encodes a memberNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of RELA, RELA. Four

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