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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression Among its related pathways are

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression Among its related pathways areThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

Among its related pathways are Endocytosis and Notch Signaling Pathways

NK2 homeobox is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman'

The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein

using NADP+ as a cofactor

including non-Hodgkin lymphoma

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression Among its related pathways areThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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