IKK gamma Polyclonal Antibody, 100ul[BT-AP10268] Thermal Control Forms a Schiff base with

Forms a Schiff base with 5-deoxyribose phosphate at abasic sites

This gene and the related gene decorin are thought to be the result of a gene duplication

Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy

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IKK gamma Polyclonal Antibody, 100ul[BT-AP10268] Thermal Control Forms a Schiff base withThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.