Phospho-CD22 (Y807) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The protein directly interacts with

The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E)

but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells

This protein also ubiquitinates the p53 tumor suppressor

Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion

a 155 aa protein

Phospho-CD22 (Y807) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The protein directly interacts withCD22, also known as Siglec 2 (sialic acid binding Ig like lectin 2) or BL CAM (B lymphocyte cell adhesion molecule), is a 130 140 kDa, B cell restricted, type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The expression of CD22 is developmentally regulated. It is expressed at low levels in the cytoplasm of pro B and pre B cells and present on the cell surface only at mature stages of B cell differentiation. Cell