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Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing RAD17 checkpoint clamp loader component

SKU: 31946149677

4.8
USD162.00 USD193.00

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Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing RAD17 checkpoint clamp loader componentBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

RAD17 checkpoint clamp loader component binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

and they may be partners in a common signaling cascade involved in tubular morphogenesis

as well as endocytosis and phagocytosis (Kato et al

also known as squamous epithelial heat shock protein 53

at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein

Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing RAD17 checkpoint clamp loader componentBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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