GCKR Polyclonal Antibody, 100ul Low retention tips The protein encoded by BAX

The protein encoded by BAX belongs to the BCL2 protein family

the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex

GO annotations related to this gene include actin binding and kinesin binding

Alternative splicing results in multiple transcripts variants

one protein-coding and the other not

GCKR Polyclonal Antibody, 100ul Low retention tips The protein encoded by BAXGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).