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p73 Polyclonal Antibody, 100ul[BT-AP06863] Nucleic Acid Extraction Many malignant cancers with poor

SKU: 32344931569

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p73 Polyclonal Antibody, 100ul[BT-AP06863] Nucleic Acid Extraction Many malignant cancers with poorTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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Description

Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase| this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis

It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues

It mediates the contraction of smooth muscles

It is an intergral membrane protein that is highly expressed in fetus

This gene encodes a protein that is a member of the dickkopf family

p73 Polyclonal Antibody, 100ul[BT-AP06863] Nucleic Acid Extraction Many malignant cancers with poorTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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