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CENPP Polyclonal Antibody, 20ul Human Genome Knockout Libraries The protein encoded by this

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CENPP Polyclonal Antibody, 20ul Human Genome Knockout Libraries The protein encoded by thisCENPP is a subunit of a CENPH (MIM 605607) CENPI (MIM 300065) associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006

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Description

The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin

There are many pseudogenes of this locus in the human genome

This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C| 1

4 leucine-rich repeats (LRRs)

Defects in protein kinase C gamma have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14)

CENPP Polyclonal Antibody, 20ul Human Genome Knockout Libraries The protein encoded by thisCENPP is a subunit of a CENPH (MIM 605607) CENPI (MIM 300065) associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006

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