HDAC3 Monoclonal Antibody, 50ul[BT-MCA0667] In vitro Assessment FST317 and FST344 containing 317

FST317 and FST344 containing 317 and 344 amino acids respectively

When overexpressed in fibroblasts

form a gene cluster in a region mapped to chromosome 2q33-q36

polymyositis or dermatomyositis

NFE4 is located in an intron of the FBXL13 gene on the opposite strand

HDAC3 Monoclonal Antibody, 50ul[BT-MCA0667] In vitro Assessment FST317 and FST344 containing 317Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase acuc apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription