SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis This magnesium-dependent enzyme catalyzes the

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions

that is a 20S core alpha subunit

Its specific function is unknown

Mutations in this gene cause autosomal dominant severe congenital neutropenia

It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins

SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis This magnesium-dependent enzyme catalyzes theThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in