EID-1 Polyclonal Antibody, 50ul Cell Biology Knockout mouse studies show defects

Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures

The protein localizes to centromeres during interphase and early prophase

thalamus and cerebral cortex

Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma

Continuous work for 5 hrs after fully charged

EID-1 Polyclonal Antibody, 50ul Cell Biology Knockout mouse studies show defectsE1A like inhibitor of differentiation 1 (EID 1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A associated cellular p300 transcriptional co activator protein. EID 1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID 1 also acetylates both histones and non histone proteins such as NCOA3 co