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BIRC2 Polyclonal Antibody, 100ul Isothermal Amplification These transcription factors are involved

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BIRC2 Polyclonal Antibody, 100ul Isothermal Amplification These transcription factors are involvedThe protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al

Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization

and thus induce the nuclear production of NF-kappaB

and it apparently protects neurons against oxidative stress and cell death

This gene has been implicated in juvenile myoclonic epilepsy

BIRC2 Polyclonal Antibody, 100ul Isothermal Amplification These transcription factors are involvedThe protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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