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NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Multiple alternatively spliced transcript variants

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NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Multiple alternatively spliced transcript variantsThis gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5 methylcytosine (m5C) at position 34 of intron containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

Multiple alternatively spliced transcript variants have been described for PPARA

Alternatively spliced transcript variants have been observed for CLIP3

Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules

tissue specificity:Expressed in normal mammary

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Multiple alternatively spliced transcript variantsThis gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5 methylcytosine (m5C) at position 34 of intron containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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