M4K2 Polyclonal Antibody, 50ul Low-speed Centrifuges nuclear transport

nuclear transport

A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia

and its interaction with p38 decreases upon cellular stress

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

but the specific function of the encoded protein is unknown

M4K2 Polyclonal Antibody, 50ul Low-speed Centrifuges nuclear transportThe protein encoded by this gene is a member of the serine threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B cell differentiation. This kinase can be activated by TNF alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor associated factor 2