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Phospho-53BP1 (S6) Polyclonal Antibody, 100ul Serological Pipets The level of expression is

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Phospho-53BP1 (S6) Polyclonal Antibody, 100ul Serological Pipets The level of expression isTP53BP1 (Tumor Protein P53 Binding Protein 1) is a Protein Coding gene. Diseases associated with TP53BP1 include riddle syndrome and ataxia telangiectasia. Among its related pathways are DNA Damage and ATM Pathway. GO annotations related to this gene include sequence specific DNA binding and p53 binding.

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Description

The level of expression is regulated by glucocorticoids

which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes

The chromosomal rearrangements are the most common genetic alterations in this gene| which result in creation of multiple fusion genes in tumourigenesis| including ALK (chromosome 2)/EML4 (chromosome 2)| ALK/RANBP2 (chromosome 2)| ALK/ATIC (chromosome 2)| ALK/TFG (chromosome 3)| ALK/NPM1 (chromosome 5)| ALK/SQSTM1 (chromosome

The product of this gene participates in physiological processes involving bile acids| conjugated steroids| and cyclic nucleotides

Pyruvate carboxylase is involved in gluconeogenesis

Phospho-53BP1 (S6) Polyclonal Antibody, 100ul Serological Pipets The level of expression isTP53BP1 (Tumor Protein P53 Binding Protein 1) is a Protein Coding gene. Diseases associated with TP53BP1 include riddle syndrome and ataxia telangiectasia. Among its related pathways are DNA Damage and ATM Pathway. GO annotations related to this gene include sequence specific DNA binding and p53 binding.

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