NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Defects in this gene are

Defects in this gene are a cause of amelogenesis imperfecta type 3 (AI3)

Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al

Marked reduction in this protein has been observed in association with Alzheimer's disease

NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Defects in this gene areThis gene encodes a member of the calcium cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone brain exchanger that can mediate a light induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury.