LSP1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Ankyrin repeat and protein kinase

Ankyrin repeat and protein kinase domain-containing protein 1 encoded by ANKK1 belongs to the Ser/Thr protein kinase family

This gene is deleted in Williams-Beuren syndrome

The protein encoded by CFLAR (CASP8 and FADD like apoptosis regulator) is a regulator of apoptosis and is structurally similar to caspase-8

characterized by the signature 7-transmembrane domain motif

Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF)

LSP1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Ankyrin repeat and protein kinaseLSP1 encodes an intracellular F actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.