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CRADD Polyclonal Antibody, 50ul Liquid Handling &Storage This gene is highly expressed

SKU: 33206039104

4.6
USD162.00 USD195.00

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CRADD Polyclonal Antibody, 50ul Liquid Handling &Storage This gene is highly expressedThis gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2 ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1 RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.

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Description

This gene is highly expressed in fetal tissues and at lower levels in few adult tissues| thus may function in signaling pathways utilized broadly during fetal development| and more selectively in adult tissues

PYPAF or Cryopyrin

The protein encoded by this gene is a member of the neurotrophin family

which is required for several steps in the initiation of protein synthesis

and left ventricular noncompaction (LVNC)

CRADD Polyclonal Antibody, 50ul Liquid Handling &Storage This gene is highly expressedThis gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2 ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1 RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.

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