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Diseases associated with C1R include immunodeficiency due to an early component of complement deficiency and c1r/c1s deficiency

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It has been shown to play a central role in the physiological regulation of programmed cell death

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CD55 Polyclonal Antibody, 20ul[BT-AP02079] Stepper Elevate your pipetting game withCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology