BIG2 Polyclonal Antibody, 50ul Cell Culture Plates Mutations have also been associated

Mutations have also been associated with non-insulin-dependent diabetes mellitus type II| an autosomal dominant disease of defective insulin secretion

Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells

by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-

The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides

The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure

BIG2 Polyclonal Antibody, 50ul Cell Culture Plates Mutations have also been associatedADP ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein (ADP ribosylation factor guanine nucleotide exchange factor 2) encoded by ARFGEF2 is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine nucleotide exchange activity and also brefeldin A inhibition.