CYH2 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction Several transcript variants encoding two

Several transcript variants encoding two different isoforms have been found for this gene

Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

MDM2 is itself transcriptionally-regulated by p53

whereas the released C-terminal fragment is an EMAP II-like cytokine

Mutations in this gene have been linked to hypophosphatasia

CYH2 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction Several transcript variants encoding twoThe protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N terminal coiled coil motif a central Sec7 domain and a C terminal pleckstrin homology (PH) domain. The coiled coil motif is involved in homodimerization the Sec7 domain contains guanine nucleotide exchange protein (GEP) activity and the PH domain interacts with phospholipids and is responsible for