ZHX2 Polyclonal Antibody, 20ul Buffers & Solutions The protein encoded by VCP

The protein encoded by VCP (valosin containing protein) is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion

It shares limited sequence similarity with iron-only bacterial hydrogenases

Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS)

A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters

It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits

ZHX2 Polyclonal Antibody, 20ul Buffers & Solutions The protein encoded by VCPThe members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor Y (NF YA) and contain two C2H2 type zinc fingers and five homeobox DNA binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.