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Cbl Polyclonal Antibody, 50ul[BT-AP01264] Modification Enzymes which is a phosphoinositide binding

SKU: 33549609458

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Cbl Polyclonal Antibody, 50ul[BT-AP01264] Modification Enzymes which is a phosphoinositide bindingCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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Description

which is a phosphoinositide binding domain

|tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium

Wolf-Hirschom syndrome

The encoded protein controls the expression of several genes

A pseudogene of this gene is found on chromosome 15

Cbl Polyclonal Antibody, 50ul[BT-AP01264] Modification Enzymes which is a phosphoinositide bindingCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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