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CD138 Polyclonal Antibody, 100ul[BT-AP01355] Biomatrix Mutations in this gene have

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CD138 Polyclonal Antibody, 100ul[BT-AP01355] Biomatrix Mutations in this gene haveThe syndecan 1 encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV 1 tat protein. The syndecan 1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell matrix interactions

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Description

Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3

the protein encoded by this gene can block TRAF2 binding to LMP1

Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation

It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain

which bind microtubules and regulate microtubule polymerization

CD138 Polyclonal Antibody, 100ul[BT-AP01355] Biomatrix Mutations in this gene haveThe syndecan 1 encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV 1 tat protein. The syndecan 1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell matrix interactions

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