Sgo1(Phospho Ser14) Polyclonal Antibody, 100ul Pipette Filler Ras family of proteins

Ras family of proteins

Mutations in this gene cause combined pituitary hormone deficiency 4

This isozyme is secreted

a disease characterized by heart defects

It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function

Sgo1(Phospho Ser14) Polyclonal Antibody, 100ul Pipette Filler Ras family of proteinsThe protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found