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F8I2 Rabbit Polyclonal Antibody, 100ul Serum The 3-phosphoinositide dependent protein kinase-1

SKU: 33894408820

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F8I2 Rabbit Polyclonal Antibody, 100ul Serum The 3-phosphoinositide dependent protein kinase-1This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h) containing F8A is repeated twice extragenically closer to the Xq telomere. Although its function is unknown the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII this gene is transcribed abundantly in a wide variety

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Description

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides

These actin isoforms regulate the contractile potential of muscle cells

A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons

CYCS encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria

F8I2 Rabbit Polyclonal Antibody, 100ul Serum The 3-phosphoinositide dependent protein kinase-1This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h) containing F8A is repeated twice extragenically closer to the Xq telomere. Although its function is unknown the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII this gene is transcribed abundantly in a wide variety

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