RUBIC Rabbit Polyclonal Antibody, 50ul Transporters encoding different isoforms with distinct

encoding different isoforms with distinct cellular localizations

This gene is clustered with another family member

An important paralog of this gene is MYO3B

and lead to the phosphorylation of glycogen synthase kinase-3

Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect

RUBIC Rabbit Polyclonal Antibody, 50ul Transporters encoding different isoforms with distinctThe protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains an N terminal RUN domain and a C terminal DUF4206 domain. The RUN domain is involved in Ras like GTPase signaling and the DUF4206 domain contains a diacylglycerol (DAG) binding like motif. Mutation in this gene results in deletion of the DAG binding like motif and causes a