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DEAF1 Rabbit Polyclonal Antibody, 100ul In vitro Assessment Knockout studies in mice suggested

SKU: 33998472322

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DEAF1 Rabbit Polyclonal Antibody, 100ul In vitro Assessment Knockout studies in mice suggestedThis gene encodes a zinc finger domain containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant mental retardation. Alternative splicing results in multiple transcript variants.

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Description

Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus

perhaps involving cytoskeletal reorganization

he 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation

This subunit may be involved in the regulation of genes by structural modulation of their chromatin| specifically in the brain

This protein also can enhance tumorigenesis by suppressing tumor cell senescence

DEAF1 Rabbit Polyclonal Antibody, 100ul In vitro Assessment Knockout studies in mice suggestedThis gene encodes a zinc finger domain containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant mental retardation. Alternative splicing results in multiple transcript variants.

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