CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays |Component of the 9-1-1 cell-cycle

|Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair

Mutations in this gene have be associated with autosomal recessive Segawa syndrome

and peripheral blood

Preferentially binds to alpha-2

This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts

CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays |Component of the 9-1-1 cell-cycleThe protein encoded by ACKR4 is a member of the G protein coupled receptor family, and is a receptor for C C type chemokines. Atypical chemokine receptor 4 has been shown to bind dendritic cell and T cell activated chemokines including CCL19 ELC, CCL21 SLC, and CCL25 TECK. A pseudogene of ACKR4 is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.