CIS Polyclonal Antibody, 50ul Virus Packaging MMP12 may play a role

MMP12 may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD)

In nucleus

The protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate

Genetic variations of this gene have been associated with Parkinson disease susceptibility

This locus encodes a BTB/POZ domain-containing protein

CIS Polyclonal Antibody, 50ul Virus Packaging MMP12 may play a roleThe protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM CSF and EPO in hematopoietic cells.