p53(Phospho Ser37) Polyclonal Antibody, 50ul Thermal Control CLN5 is one of eight

CLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL)

with highest expression in fetal lung

This gene encodes a long chain base subunit of serine palmitoyltransferase

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity

angiogenesis and cell migration

p53(Phospho Ser37) Polyclonal Antibody, 50ul Thermal Control CLN5 is one of eightThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.