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TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation The transmembrane protein encoded by

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TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation The transmembrane protein encoded byNKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory

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Description

The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels

Belongs to the V-ATPase V0D/AC39 subunit family

Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins

It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins

tissue specificity:Widely expressed with highest levels in brain

TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation The transmembrane protein encoded byNKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory

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