HEN1/2 Polyclonal Antibody, 50ul Molecular Biology non-erythrocytic 1) is one member

non-erythrocytic 1) is one member of a family of beta-spectrin genes

it is normally found in the nucleus except during mitosis

The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol

The encoded protein undergoes a change in conformational state and activity

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

HEN1/2 Polyclonal Antibody, 50ul Molecular Biology non-erythrocytic 1) is one memberThe helix loop helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCL.