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Mutations in this gene are associated with acute myeloid leukemia

This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors

consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III)

ERBeta Polyclonal Antibody, 100ul[BT-AP03082] Buffers & Solutions reliable kitESR2 encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N terminal DNA binding domain and C terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta estradiol or related ligands, the encoded protein forms homo or hetero dimers that interact with specific DNA sequences to activate transcription. Some